目 次
原著論文要旨
[5]thiaheterohelicene
as a probe.[PDF(48KB)].................. 1
Hiroko Nakagawa(中川弘子)，Yuuki Kobori(小堀裕紀)，Maiko Yoshida
(吉田麻衣子)，and Koh-ichi
Yamada(山田紘一)
Chiral
Recognition of Thiaheterohelicenes by Alkyl β-D-Pyranoside
Micelles.
Influence
of Extension of Helix.[PDF(52KB)]............... 2
Hiroko Nakagawa(中川弘子)， Kanae Gomi(五味香苗)，and Koh-ichi
Yamada
（山田紘一）
Spontaneous Chirality
Conversion of [5]Thiaheterohelicene in Charge-Transfer
Complexes in SDS Micelles.[PDF(49KB)]...... 3
Hiroko Nakagawa(中川弘子)， Yuuki Kobori(小堀裕紀)，
and Koh-ichi Yamada(山田紘一)
Total Synthesis of (±)-Stemodinone via an Efficient Ring-Exchange Strategy[PDF(66KB)]............................... 4
Tetsuaki Tanaka，Kazuo Murakami，Atsushi Kanda, Debasis Patra，
Sachiko Yamamoto，Norifumi Satoh，Sang-Won Kim(金
相元)，S.M.Abdur Rahman,
Hiroaki Ohno，and Chuzo Iwata
HETEROCYCLIZATION OF 4-TRIFLUOROACETYL-1,3-OXAZOLIUM-5-OLATES
WITH 1,4-BIS-NUCLEOPHILES[PDF(65KB)]............................... 5
Masami Kawase(河瀬雅美)， Hiromi Koiwai(小岩井広美)， Toru Tanaka(田中 享)，
Satoru Tani(谷
覺)，and Hiroshi Miyamae
Convenient Synthesis of 4-Trifluoromethyl-Substituted Imidazole Derivatives[PDF(60KB)]......... 6
Masami Kawase(河瀬雅美)，Setsuo Saito(齋藤節生) and
Teruo Kurihara
Trifluoromethyl Ketone-based Inhibitors of Apoptosis in Cerebellar
Granule Neurons[PDF(60KB)]............... 7
Masami Kawase(河瀬雅美)，Katsuyoshi Sunaga(須永克佳)，Satoru Tani(谷 覺),
Masayuki Niwa, and Toshihiko Uematsu
Antimicrobial activity of trifluoromethyl ketones and their synergism
with promethazine[PDF(59KB)]............................... 8
Masami Kawase(河瀬雅美)，Noboru Motohashi，Hiroshi Sakagami，Taisei Kanamoto，
Hideki Nakashima，Lajos Ferenczy，Kristina Wolfard，Csilla Miskolci and
Joseph Molnar
Antimicrobial Activity of New Coumarin Derivatives[PDF(62KB)]......... 9
Masami Kawase(河瀬雅美)，Bharat Varu，Anamik Shah，Noboru Motohashi，
Satoru Tani(谷 覺)，Setsuo Saito(齋藤節生)，Sanchayita Debnath，S. Mahapatra，
Sujata G. Dastidar and A. N. Chakrabarty
Enhanced antibacterial effect of erythromycin in the presence of
3,5-dibenzoyl-1,4-dihydropyridines[PDF(65KB)]...............................
10
Gyongyi Gunics，Noboru Motohahsi，Joseph Molnar，Ssndor Farkas，
Masami Kawase(河瀬雅美)，Setsuo Saito(齋藤節生)，and Anamik Shah
Biological activity of Kiwifruit peel extracts[PDF(58KB)]...............
11
Noboru Motohashi，Yoshiaki Shirataki(白瀧義明)，Masami Kawase(河瀬雅美)，
Satoru Tani(谷 覺)，Hiroshi Sakagami，Kazue Satoh，Teruo Kurihara，
Hideki Nakashima，Kristina Wolfard，Csilla Miskolci，and Joseph Molnar
Biological activity of a fruit vegetable, "Anastasia Green", a species of sweet pepper[PDF(57KB)]................
12
Noboru Motohashi，Teruo Kurihara，Hidetsugu Wakabayashi，Mikako Yaji，
Ilona Mucsi，Joseph Molnar，Shichiro Maruyama，Hiroshi Sakagami，
Hideki Nakashima，Satoru Tani(谷 覺)，Yoshiaki Shirataki(白瀧義明)，
and Masami Kawase(河瀬雅美)
4-(2-Aminoethylamino)-7H-benz[de]benzimidazo[2,1-a]isoquinoline-7-one
as a
Highly Sensitive Fluorescent Labeling Reagent for Carnitine[PDF(55KB)]...............................
13
Ken-ichi Nakaya，Toshiyuki Tanaka，Yoshiaki Shirataki (白瀧義明)，
Hisayoshi Shiozaki，Kazumasa Funabiki，Katsuyoshi Shibata1 and Masaki Matsui
Comparison of Antioxidative and Chelating Effects of Daidzein and Daidzin on
Protein Oxidative Modification by Copper In Vitro[PDF(51KB)]...............................
14
Shizuo Toda and Yoshiaki Shirataki (白瀧義明)
In Vitro Biological Activity of Prenylflavanones[PDF(58KB)].............................
15
Yoshiaki Shirataki(白瀧義明)，Noboru Motohashi，Satoru Tani(谷 覺)，
Hiroshi Sakagami，Kazue Satoh，Hideki Nakashima，S. K. Mahapatra，
Kumkum Ganguly，Sujata G. Dastidar and A. N. Chakrabarty
Stilbenoids in Lianas of Gnetum parvifolium[PDF(55KB)].........
16
Toshiyuki Tanaka，Ibrahim Iliya，Tetsuro Ito，Miyuki Furusawa，
Ken-ichi Nakaya，Munekazu Iinuma，Yoshiaki Shirataki(白瀧義明)，
Nobuyasu Matsuura，Makoto Ubukata，Jin Murata，Fumio Simozono
and Kazunori Hirai
Inhibitory Effects of Echinoisoflavanone and Sophoraisoflavanone D in
Sophora chrysophylla Seem on Lipid Peroxidation of Mice Brain Homogenate by
Interaction of Ferrous Ion and Hydrogen Peroxide In Vitro[PDF(52KB)]...............................
17
Shizuo Toda and Yoshiaki Shirataki(白瀧義明)
Monitoring of MRP-like Activity in Human Erythrocytes: Inhibitory Effect of Isoflavones [PDF(59KB)].. 18
Malgorzata Bobrowska-Hagerstrand，Anna Wrobel，Blazej Rychlik，Grzegorz Bartosz，
Thomas Soderstrom，Yoshiaki Shirataki(白瀧義明)，Noboru Motohashi，
Joseph Molnar，Krystyna Michalak and Henry Hagerstrand
Antioxidative effects of Dibenzo-α-pyrones in Fruits of Trapa natans on Lipid
Peroxidation[PDF(51KB)]......
19
Yoshiaki Shirataki(白瀧義明)
and Shizuo Toda
Four New Glucosides of Stilbene Oligomers from the Stem of Gnetum gnemonoides[PDF(55KB)]...
20
Ibrahim Iliya，Toshiyuki Tanaka，Miyuki Furusawa，Zulfiqar Ali，
Ken-ichi Nakaya，Munekazu Iinuma，Yoshiaki Shirataki(白瀧義明)，Jin Murata
and Dedy Darnaedi
Relationship between Cytotoxic Activity and Radical Intensity of Isoflavones from
Sophora Species[PDF(59KB)]...............
21
Yoshiaki Shirataki(白瀧義明)，Satoru Tani(谷 覺)，Hiroshi Sakagami，Kazue Satoh，
Hideki Nakashima，Kazuyo Gotoh and Noboru Motohashi
Antimicrobial Activity of Prenylflavanones[PDF(56KB)].............................
22
Sujata G. Dastidar, S. K. Mahapatra, Kumkum Ganguly, A. N. Chakrabarty,
Yoshiaki Shirataki(白瀧義明)，and Noboru Motohashi
Reactivity of 2-methylene-1,3-dicarbonyl compounds: catalytic enantioselective
Diels-Alder reaction[PDF(50KB)]...............................
23
Masashige Yamauchi(山内昌茂)，Takashi Aoki(青木隆)，Ming-Zhu Li(李明洙)
and Yuko Honda(本田裕子)
Diastereoselective synthesis of 2-alkylated 4-silyloxyproline esters[PDF(54KB)]...............................
24
Tatsunori Sato，Satomi Kawasaki，Nobuo Oda，Shoko Yage,
Serry A. A. El Bialy，Jun'ichi Uenishi，Masashige Yamauchi(山内昌茂)
and Masazumi Ikeda
Reactivity of 2-Methylene-1,3-dicarbonyl Compounds. 1,3-Dipolar Cycloaddition
Reaction with Diazoacetate[PDF(47KB)]...............................
25
Masashige Yamauchi(山内昌茂)，and Masahiko
Yajima(矢嶋優彦)
A
New and Convenient Synthesis of 3-Aryl-3-hydroxyisoindol-1-ones and Their
Aza
Analogs[PDF(53KB)]......
26
Yuko
Saito(斉藤優子),
Takeshi Sakamoto(坂本武史),
Yasuo Kikugawa(菊川靖雄)
A
new intramolecular migration of the imino group of O-arylketoximes to the aryl
group under the Beckmann condition[PDF(53KB)]............ 27
Yasuo
Kikugawa(菊川靖雄), Chiho Tsuji(辻千穂), Etsuko Miyazawa(宮沢悦子)
and
Takeshi Sakamoto(坂本武史)
Reaction
of Phenylhydrazines with Arenes in the Presence of Aluminium Trichloride[PDF(53KB)].......... 28
Atsushi
Ohwada(大和田淳), Shigeru Nara(奈良繁), Takeshi Sakamoto(坂本武史)
and
Yasuo Kikugawa(菊川靖雄)
Synthesis
of Carbazoles from N-(N,N-Diarylamino)phthalimides with
Aluminum
Chloride
via Diarylnitrenium Ions[PDF(52KB)].......................
29
Yasuo
Kikugawa (菊川靖雄),
Yutaka Aoki (青木豊),
and Takeshi Sakamoto (坂本武史)
Synthesis
of 4-Oxepanones by the Lewis Acid-Promoted Ring-Expansion
Reaction
of Cyclopropapyranones [PDF(55KB)]....................... 30
Yoshiaki
Sugita(杉田義昭），Chikasa
Kimura(木村爾沙)，Hiroki Hosoya(細谷弘樹)，
Shiori
Yamadoi (山土井しおり)，and Ichiro Yokoe(横江一朗)
Diastereoselective
Ring-Expansion Reaction of Methanochromanone with
Aldehydes:
Formation of trans-Fused Tetrahydrofuro[2,3-b][1]benzopyranones
and
Their
Isomerization[PDF(58KB)]...............................
31
Yoshiaki
Sugita(杉田義昭)，Kazuyoshi Kawai(川井一良)，and Ichiro Yokoe(横江一朗)
Synthesis
of Trisubstituted 4-Oxepanones by the Lewis Acid-Promoted
Three-Component
Ring-Expansion Reaction of Cyclopropapyranones,
Silyl
Enolates and Glyoxylates[PDF(56KB)]...............................
32
Yoshiaki
Sugita(杉田義昭)，Chikasa Kimura(木村爾沙)，and Ichiro Yokoe(横江一朗)
Reaction
of 3-Iodochromone with Nucleophiles 3. Formation of
2-Aminomethylene-3(2H)-benzofuranones
by the Reaction with Secondary Amines[PDF(55KB)]................... 33
Yoshiaki
Sugita(杉田義昭)，Takako Iwaki(岩木貴子)，Misaki Okamoto(岡本美咲)，
and
Ichiro Yokoe(横江一朗)
Lewis
Acid-Promoted Cycloaddition Reaction of Cyclopropanes with Allylsilanes[PDF(56KB)].... 34
Yoshiaki
Sugita(杉田義昭)，Shiori Yamadoi(山土井しおり)，Hiroki Hosoya (細谷弘樹)，
and
Ichiro Yokoe(横江一朗)
Cytotoxic
Activity of 5-Benzoylimidazole and Related Compounds against
Human
Oral Tumor Cell Lines [PDF(55KB)]
35
Kuniko
Terasawa(寺沢邦子)，Yoshiaki Sugita(杉田義昭)，Ichiro Yokoe (横江一朗)，
Seiichiro
Fujisawa，and
Hiroshi Sakagami
Cytotoxic
Activity of Benzothiepins against Human Oral Tumor Cell Lines[PDF(54KB)]............................... 36
Yoshiaki
Sugita(杉田義昭)，Hiroki Hosoya(細谷弘樹)，Kuniko Terasawa(寺沢邦子)，
Ichiro
Yokoe(横江一朗)，Seiichiro Fujisawa，and Hiroshi Sakagami
Cytotoxic
Activity of 2-Aminomethylene-3(2H)-benzofuranones against Human
Oral
Tumor Cell Lines[PDF(54KB)]...............................
37
Kuniko
Terasawa(寺沢邦子)，Yoshiaki Sugita(杉田義昭)，Ichiro Yokoe (横江一朗)，
Seiichiro
Fujisawa，and
Hiroshi Sakagami
Analytical
Occurrence of aminopropylhomospermidine as the major cellular polyamine in a
halophilic, phototrophic alpha proteobacterium, Rhodothalassium salexigens[PDF(52KB)]...............................
38
Koei Hamana，Masaru Niitsu(新津 勝)，and Keijiro Samejima(鮫島啓二郎)
Large production of an aromatic amine, 2-phenylethylamine, in a psychrophilic
marine bacterium, Psychroflexus torquis[PDF(51KB)]...............................
39
Koei Hamana，and Masaru Niitsu(新津 勝)
Biochemistry/Molecular
Biology
Regulation
of estrogenic and nuclear factor κ B functions by
polyamines and their
role
in polyamine analog-induced apoptosis of breast cancer cells.[PDF(56KB)]..................... 40
Neha Shah，TJ Thomas，John S Lewis，Carolyn M Klinge，
Akira
Shirahata(白幡 晶)，Celine Gelinas and Thresia
Thomas
A
Molecular Beacon Strategy for Thermodynamic Characterization of Triplex
DNA:
Triplex Formation at the Promoter Region of Cyclin D1[PDF(55KB)].......................... 41
Thomas
Antony, Thresia Thomas，Leonard
H. Sigal，Akira
Shirahata(白幡 晶)，
and T. J.
Thomas
DNA
Condensation by Polyamines: A Laser Light Scattering Study of Structural
Effects.[PDF(56KB)]..................
42
Veena
Vijayanathan，Threia
Thomas，Akira
Shirahata(白幡 晶)，and T. J. Thomas
Polyamine
Cytotoxicity in the Presence of Bovine Serum Amine Oxidase[PDF(52KB)]... 43
Shahana
Sharmin, Kaori Sakata, Keiko Kashiwagi, Shiro Ueda, Satoko Iwasaki,
Akira
Shirahata（白幡 晶）,
Kazuei Igarashi
Accumulation
of Medium Chain Acyl-CoAs during b-Oxidation of Long Chain
Fatty
Acid by Isolated Peroxisomes from Rat Liver [PDF(54KB)]............................... 44
Fumie
Hashimoto(橋本フミ惠)，Yasuko Furuya(古屋泰子)，and
Hidenori
Hayashi(林 秀徳)
ＱＯＬに対するアロマセラピー効果とその可能性[PDF(50KB)]...............................
45
Takeo Kawaguchi (川口 健夫)
Effect of Glucocorticoid on Expression of Rat MUC5AC mRNA in Rat Gastric
Mucosa in Vivo and in Vitro[PDF(56KB)]...............................
46
Toru Tanaka (田中享)，Taketo Kobayashi(小林丈人)，Katsuyoshi Sunaga (須永克佳)，
and Satoru Tani(谷 覺)
Comparison of the
elimination between perfluorinated fatty acids with different
carbon chain
length in rats[PDF(53KB)]...............................
47
Naomi Kudo(工藤なをみ)，Erika Suzuki(鈴木恵里春)，Masanori Katakura
(片倉賢紀)，Kohtaro Ohmori(大森耕太郎)，Rie Noshiro(野城理絵) and
Yoichi Kawashima(川嶋洋一)
Effects of
perfluorooctanoic acid on the synthesis of phospholipids in the liver of
mice fed a dietary
soy bean oil, perilla oil or fish oil[PDF(53KB)]............................... 48
Naomi Kudo(工藤なをみ) and Yoichi
Kawashima(川嶋洋一)
Metabolic
alterations by clofibric acid in the formation of molecular species of
phosphatidylcholine
in the liver of rats[PDF(55KB)]............................... 49
Hiroki Mizuguchi，Naomi Kudo(工藤なをみ)，and Yoichi
Kawashima(川嶋洋一)
Effects of
dehydroepiandrosterone on oleic acid formation in the liver of rats,
mice and guinea
pigs[PDF(54KB)]...............................
50
Koich Imai，Naomi Kudo(工藤なをみ)，Matajirou Koyama，Akira Shirahata
(白幡晶)and Yoichi
Kawashima(川嶋洋一）
Prostaglandin E2 (EP1) receptor agonist-induced DNA synthesis and proliferation
in primary cultures of adult rat hepatocytes: The involvement of transforming
growth factor-α.[PDF(65KB)]...............................
51
Mitsutoshi Kimura(木村光利)，Sachie Osumi(大澄幸恵)，and Masahiko Ogihara
(荻原政彦)
Glycyrrhizin and some analogues induce growth of primary cultured adult rat
hepatocytes via epidermal growth factor receptors.[PDF(62KB)]...............................
53
Mitsutoshi Kimura(木村光利)，Hideo Inoue，Kazuhiro Hirabayashi，
Hideshi Natsume(夏目秀視)，and Masahiko Ogihara(荻原政彦)
Tolerance to
analgesia dependence liability by topical application of
dihydroetorphine
to hairless rats[PDF(51KB)]...............................
55
Satoshi Ohmori(大森悟史)，Liang Fang(方 亮)，Masami Kawase(河瀬雅美)，
Setsuo Saito(齋藤節生)，Yasunori Morimoto(森本雍憲)
Pharmaceutical
Transdermal
microparticle delivery by a supersonic-HeliosTM gun system[PDF(55KB)]............................... 56
Jin Yi，Uchida Masaki(内田昌希)，Wang Cheng-fa，Natsume Hideshi
(夏目秀視)，Sugibayashi Kenji(杉林堅次)，Morimoto Yasunori(森本雍憲)
A protective
effect against undesirable increase of dihydroetorphine permeation
through damaged
skin by using pressure-sensitive adhesive tape with an
ethylene-vinyl
acetate co-polymer membrane[PDF(53KB)]............................... 57
Satoshi Ohmori(大森悟史)，Yohei Sugiyama(杉山洋平)，and
Yasunori Morimoto(森本雍憲)
Estimation
of Absorption Rate of α-Human Atrial
Natriuretic Peptide from the
Plasma
Profile and Diuretic Effect after Intranasal Administration to Rats[PDF(54KB)]............................... 58
Misao Miyamoto，Tadashi Tsukune(築根忠司)，Seiichi Hori(堀 聖一)，
Teruaki Hayashi，Hideshi Natsume(夏目秀視)，Kenji Sugibayashi(杉林堅次）
and Yasunori
Morimoto(森本雍憲)
Improved nasal
absorption of drugs using poly-L-arginine: effects of concentration
and molecular
weight of poly-L-arginine on thenasal absorption of fluorescein
isothiocyanate-dextran
in rats[PDF(59KB)]...............................
59
Misao Miyamotoa,
Hideshi Natsume(夏目秀視)，Satoko Iwata(岩田聡子)，
Kazuo Ohtake(大竹一男)，Masatoshi
Yamaguchic，Daisuke Kobayashi(小林大介)，
Kenji Sugibayashi(杉林堅次)，Motoaki Yamashinad，Yasunori Morimoto(森本雍憲)
Effect of
poly-L-arginine on the nasal absorption of FITC-dextran of different
molecular weights
and recombinant human granulocyte colony-stimulating
factor (rhG-CSF)
in rats[PDF(59KB)]...............................
61
Misao Miyamotoa，Hideshi Natsume(夏目秀視)，Izumi Satoh(佐藤いづみ)，
Kazuo Ohtake(大竹一男)，Masatoshi
Yamaguchid，Daisuke Kobayashi(小林大介)，
Kenji Sugibayashi(杉林堅次)，Yasunori Morimoto(森本雍憲)
Pharmacokinetic
and pharmacodynamic evaluations of a potent analgesic
dihydroetorphine,
in hairless rat[PDF(53KB)]...............................
63
Satoshi Ohmori，Teruaki Hayashi，Masami Kawase(河瀬雅美)，Setsuo Saito
(斎藤節生)，Yasunori Morimoto(森本雍憲)
N-Acetyltransferase2
Genotype Correlated with Isoniazid Acetylation in Japanese
Tuberculous
Patients. [PDF(60KB)]............................... 64
T. Kita，Y. Tanigawara，S. Chikazawa，H. Hatanaka，T. Sakaeda，F. Komada
(駒田富佐夫)，S. Iwakawa，and K. Okumura
Identification of
N-Acetyltransferase 2 and CYP2C19 Genotypes for Hair, Buccal
Cell Swabs, or
Fingernails Compared with Blood. [PDF(54KB)]............................... 66
Y. Tanigawara，T. Kita，M. Hirono，T. Sakaeda，F. Komada(駒田富佐夫) and
K Okumura
CYP2C19
Genotype Related Effect of Omeprazole on Intragastric pH and
Antimicrobial Stability.[PDF(58KB)]............................... 67
T.
Kita，Y. Tanigawara，N. Aoyama，T. Hohda，Y. Saijoh，F. Komada(駒田富佐夫)，
T.
Sakaeda，K. Okumura，T. Saka，and M. Kasuga
Adrenergic
Receptor Genotype-Related Changes in cAMP Levels in peripheral
Blood Mononuclear
Cells after Multiple-Dose Oral Procaterol.[PDF(55KB)]...............................
68
H. Makimoto，T. Sakaeda，K. Nishiguchi，T. Kita，T. Sakai，F. Komada(駒田富佐夫)，
and K. Okumura
Electric field
analysis on the improved skin concentration of benzoate by
electroporation [PDF(52KB)]............................... 69
Kenji Sugibayashi(杉林堅次)，Maki Yoshida(吉田牧)，Kenji Mori，
Tetsuya Watanabe(渡邉哲也)，Tetsuya Hasegawa(長谷川哲也)
Potential
usefulness of solubility index for prediction of the skin permeation rate
of 5-IMSN from
pressure-sensitive adhesive tape[PDF(51KB)]............................... 70
Kimihiro Sato(佐藤公洋)， Naomi
Mitsui(三井直美)，Tetsuya Hasegawa(長谷川哲也)，
Kenji Sugibayashi(杉林堅次)，Yasunori Morimoto(森本雍憲)
Utility of the
Three-Dimensional Cultured Human Skin Model as a Tool to
Evaluate Skin
Permeation of Drugs[PDF(53KB)]...............................
71
Tetsuya Watanabe(渡邉哲也)，Tetsuya Hasegawa(長谷川哲也)，Hidekazu Takahashi，
Takuya Ishibashi，Kozo Takayama，Kenji Sugibayashi(杉林堅次)
Effect of
Penetration Enhancers on the Permeation of Drugs across a
Three-Dimensional
Cultured Human Skin Model: Comparison with the
Effects Using
Excised Hairless Rat Skin[PDF(53KB)]............................... 72
Tetsuya Watanabe(渡邉哲也)，Tetsuya Hasegawa(長谷川哲也)，Hidekazu Takahashi，
Takuya Ishibashi，Kenji Sugibayashi(杉林堅次)
口頭発表及びシンポジウム[PDF(235KB)]................... 75
著書・総説・Proceedings[PDF(69KB)]............................ 95
学位論文要旨............................... 101
安定同位体標識ポリアミンを利用する方法論の開発と応用[PDF(64KB)]............................... 101
許 泳吉
薬物の皮膚透過並びに皮膚刺激の評価材料としての三次元培養ヒト皮膚モデルの有用性[PDF(58KB)]............................... 103
渡邉哲也
大森悟史
高分子薬物の鼻粘膜からの吸収に関する研究[PDF(54KB)]............................... 108
宮本 操
戸張彰彦
大学院薬学研究科修士論文要旨[PDF(174KB)]............................... 115
薬学専攻
チロシナーゼ阻害作用を有するフェノール類の合成............................... 115
中野文子
Acetanilide誘導体とHypervalent lodine化合物との反応............................... 116
伊藤直樹
N-Acylaminophthalimide類とPhenyliodine(III) Bis(trifluoroacetate)との反応............................... 116
長島 章
ミセルを反応場とする両親媒性ヘリセンのキラリティーの誘起と変換............................... 117
高市康宏
ヘリセンをプローブとするグリセロリン脂質二分子膜によるキラル識別............................... 118
吉田麻衣子
結晶場によるキラリティーの制御―ラセミ結晶とエナンチオマ一結晶―............................... 118
吉野 順
ＨＰＬＣを用いる脱炭酸化Ｓ－アデノシルメチオニンの高感度定量法の開発............................... 119
岩崎聖子
グアニジノ化合物投与によるＨＴＣ細胞における増殖とポリアミン量への影響............................... 120
岡本政治
蛍光基質を用いたＨＰＬＣによるスペルミジン／スペルミン－Ｎ１－
アセチル移転酵素活性測定法の開発............................... 121
深澤一昭
ペルフルオロ脂肪酸の体内動態における血漿アルミブンの影響............................... 121
佐藤靖典
ペルフルオロ脂肪酸の排泄における動物種差および性差の検討............................... 122
住谷文須紗
脂肪酸伸長酵素および不飽和化酵素に対するフッ素化脂肪酸の影響............................... 123
外山智章
ポリプロピレングリコールを分散媒として用いたデンプンマイクロスフィアの調製法............................... 123
篠原克典
薬物の粘膜吸収における細胞間隙透過性の評価に関する研究............................... 125
原田園子
薬物の種々媒体中における拡散性の評価............................... 126
持田純子
ワルファリンとブコロームの併用とその有効性及び有用性について............................... 126
羽田乃武子
パラベン類の皮膚透過に及ぼす高分子添加剤の影響とその解析............................... 126
金 素安
サリチル酸の皮膚透過ならびに皮膚中および筋肉内濃度に及ぼす灸処理の影響............................... 127
田澤悠子
皮膚中代謝及び担体輸送の研究における三次元培養ヒト皮膚モデルの有用性に関する検討............................... 128
松本かおり
β２受容体プロモーター領域における遺伝子多型の頻度............................... 128
岩崎鉄尚
スタチン系抗高脂血症薬投与による血清コレステロールとドリコールの濃度変化............................... 129
小泉宜史
不死化ヒト胎盤絨毛細胞の酵素活性とホルモン分泌に対するペルオキシソーム増殖剤
ゲンフィブロジル、クロフィブリン酸の影響............................... 130
小口敬伸
健康食品に関する実態調査............................... 131
山﨑理恵
白血病治療の支持療法におけるＨ２ブロッカー選択............................... 131
赤津 勲
In vitro 経皮吸収試験法―OECDガイドライン（案）―における皮膚integrity
および物質収支の評価に関する研究............................... 132
土肥大典
著者索引[PDF(98KB)]....................... 133