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＜電子ブック＞
Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics : Homogeneous and Heterogeneous Approaches / by Panos Macheras, Athanassios Iliadis
(Interdisciplinary Applied Mathematics. ISSN:21969973 ; 30)

版	1st ed. 2006.
出版者	(New York, NY : Springer New York : Imprint: Springer)
出版年	2006
本文言語	英語
大きさ	XX, 444 p : online resource
著者標目	*Macheras, Panos author Iliadis, Athanassios author SpringerLink (Online service)
件　名	LCSH:Biomathematics LCSH:Pharmacology LCSH:Biophysics LCSH:Biomedical engineering LCSH:Biochemistry LCSH:Mathematics FREE:Mathematical and Computational Biology FREE:Pharmacology FREE:Biophysics FREE:Biomedical Engineering and Bioengineering FREE:Biochemistry FREE:Applications of Mathematics
一般注記	Basic Concepts -- The Geometry of Nature -- Diffusion and Kinetics -- Nonlinear Dynamics -- Modeling in Biopharmaceutics -- Drug Release -- Drug Dissolution -- Oral Drug Absorption -- Modeling in Pharmacokinetics -- Empirical Models -- Deterministic Compartmental Models -- Stochastic Compartmental Models -- Modeling in Pharmacodynamics -- Classical Pharmacodynamics -- Nonclassical Pharmacodynamics The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. This timely and useful book will appeal to graduate students and researchers in pharmacology, pharmaceutical sciences, bioengineering, and physiology HTTP:URL=https://doi.org/10.1007/0-387-31910-7

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