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＜電子ブック＞
Mathematical Models for Therapeutic Approaches to Control Psoriasis / by Priti Kumar Roy, Abhirup Datta
(SpringerBriefs in Mathematical Methods. ISSN:23650834)

版	1st ed. 2019.
出版者	(Singapore : Springer Nature Singapore : Imprint: Springer)
出版年	2019
本文言語	英語
大きさ	XVII, 89 p. 33 illus., 29 illus. in color : online resource
著者標目	*Roy, Priti Kumar author Datta, Abhirup author SpringerLink (Online service)
件　名	LCSH:Biomathematics LCSH:Mathematical models LCSH:Mathematics LCSH:Medicine, Preventive LCSH:Health promotion FREE:Mathematical and Computational Biology FREE:Mathematical Modeling and Industrial Mathematics FREE:Applications of Mathematics FREE:Health Promotion and Disease Prevention
一般注記	Chapter 1. Introduction -- Chapter 2. Basic MathematicalModel on Immunopathogenic Plaque of Psoriasis -- Chapter 3.Release of Cytokine and Its Control during the Formation of Psoariasis -- Chapter 4. Regulating Growth of Keratinocytes through Feedback Mechanism with Delay Effect in Psoriatic System -- Chapter 5. Control of Psoriatic System for logistic T-Cell Proliferation -- Chapter 6. Incidental Effect of Half-Saturation on the Psoriatic Pathogenesis -- Chapter 7. Inhibition of Excessive Keratinocyte Growth in Psoriasis using Drugs Cyclosporin and FK506 -- Chapter 8. Fractional Approach of the Formation of Psoriasis during Release of Cytokines -- Chapter 9. Fractional Approach for Incidental Effect of Half-Saturation on the Psoriatic Pathogenesis -- Chapter 10. Fractional Approach for the Inhibition of Excessive Keratinocyte Growth in Psoriasis using Drugs Cyclosporin and FK506 This book discusses several mathematical models highlighting the disease dynamics of psoriasis and its control. It explains the control of keratinocyte concentration through a negative feedback mechanism and the effect of including a realistic time delay in that system. The effect of cytokine release is described in a mathematical model of psoriasis and further elucidated in two different mathematical pathways: the ordinary differential equation model system, and the fractional-order differential equation model system. The book also identifies the role of CD8+ T-cells in psoriasis by investigating the interaction between dendritic cells and CD8+ T-cells. Presenting an approach to control the fractional-order system to prevent excess production of keratinocyte cell population, the book is intended for researchers and scientists in the field of applied mathematics, health informatics, applied statistics and qualitative public health, as well as bio-mathematicians interested in the mathematical modeling of autoimmune diseases like psoriasis HTTP:URL=https://doi.org/10.1007/978-981-13-9020-3

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