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＜電子ブック＞
Mathematical Grammar of Biology / by Michel Eduardo Beleza Yamagishi
(SpringerBriefs in Mathematics. ISSN:21918201)

版	1st ed. 2017.
出版者	(Cham : Springer International Publishing : Imprint: Springer)
出版年	2017
本文言語	英語
大きさ	XII, 82 p. 19 illus., 17 illus. in color : online resource
著者標目	*Yamagishi, Michel Eduardo Beleza author SpringerLink (Online service)
件　名	LCSH:Population genetics LCSH:Bioinformatics LCSH:Biology -- Philosophy  全ての件名で検索 FREE:Population Genetics FREE:Computational and Systems Biology FREE:Philosophy of Biology
一般注記	Chapter 01- Introduction -- Chapter 02- Modeling Human Nucleotide Frequencies -- Chapter 03- Expanding the Grammar of Biology -- Chapter 04 - "In God We Trust; All Others, Bring Data."- References This seminal, multidisciplinary book shows how mathematics can be used to study the first principles of DNA. Most importantly, it enriches the so-called “Chargaff’s grammar of biology” by providing the conceptual theoretical framework necessary to generalize Chargaff’s rules. Starting with a simple example of DNA mathematical modeling where human nucleotide frequencies are associated to the Fibonacci sequence and the Golden Ratio through an optimization problem, its breakthrough is showing that the reverse, complement and reverse-complement operators defined over oligonucleotides induce a natural set partition of DNA words of fixed-size. These equivalence classes, when organized into a matrix form, reveal hidden patterns within the DNA sequence of every living organism. Intended for undergraduate and graduate students both in mathematics and in life sciences, it is also a valuable resource for researchers interested in studying invariant genomic properties HTTP:URL=https://doi.org/10.1007/978-3-319-62689-5

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