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A Guide to Numerical Modelling in Systems Biology / by Peter Deuflhard, Susanna Röblitz
(Texts in Computational Science and Engineering. ISSN:2197179X ; 12)

1st ed. 2015.
出版者 (Cham : Springer International Publishing : Imprint: Springer)
出版年 2015
本文言語 英語
大きさ X, 168 p. 42 illus., 33 illus. in color : online resource
著者標目 *Deuflhard, Peter author
Röblitz, Susanna author
SpringerLink (Online service)
件 名 LCSH:Differential equations
LCSH:Mathematics
LCSH:Biomathematics
LCSH:Computer simulation
LCSH:Mathematical physics
FREE:Differential Equations
FREE:Applications of Mathematics
FREE:Mathematical and Computational Biology
FREE:Computer Modelling
FREE:Theoretical, Mathematical and Computational Physics
一般注記 Preface -- Outline -- ODE Models for Systems Biological Networks -- Numerical Simulation of ODE Models -- Parameter Identification in ODE Models -- Appendix -- Software -- Index
This book is intended for students of computational systems biology with only a limited background in mathematics. Typical books on systems biology merely mention algorithmic approaches, but without offering a deeper understanding. On the other hand, mathematical books are typically unreadable for computational biologists. The authors of the present book have worked hard to fill this gap. The result is not a book on systems biology, but on computational methods in systems biology. This book originated from courses taught by the authors at Freie Universität Berlin. The guiding idea of the courses was to convey those mathematical insights that are indispensable for systems biology, teaching the necessary mathematical prerequisites by means of many illustrative examples and without any theorems. The three chapters cover the mathematical modelling of biochemical and physiological processes, numerical simulation of the dynamics of biological networks, and identification of model parameters by means of comparisons with real data. Throughout the text, the strengths and weaknesses of numerical algorithms with respect to various systems biological issues are discussed. Web addresses for downloading the corresponding software are also included.  
HTTP:URL=https://doi.org/10.1007/978-3-319-20059-0
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Springer eBooks 9783319200590
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データ種別 電子ブック
分 類 LCC:QA370-380
DC23:515.35
書誌ID 4000117557
ISBN 9783319200590

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