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＜電子ブック＞
Stochastic Approaches for Systems Biology / by Mukhtar Ullah, Olaf Wolkenhauer

版	1st ed. 2011.
出版者	(New York, NY : Springer New York : Imprint: Springer)
出版年	2011
大きさ	XXXII, 290 p : online resource
著者標目	*Ullah, Mukhtar author Wolkenhauer, Olaf author SpringerLink (Online service)
件　名	LCSH:Probabilities LCSH:Bioinformatics LCSH:Biomathematics FREE:Probability Theory FREE:Computational and Systems Biology FREE:Mathematical and Computational Biology FREE:Bioinformatics
一般注記	Preface.-  Acknowledgements -- Acronyms, notation -- Matlab functions, revisited examples -- Introduction -- Biochemical reaction networks -- Randomness -- Probability and random variables -- Stochastic modeling of biochemical networks -- The 2MA approach -- The 2MA cell cycle model -- Hybrid Markov processes -- Wet-lab experiments and noise -- Glossary This textbook focuses on stochastic modelling and its applications in systems biology. In addition to a review of probability theory, the authors introduce key concepts, including those of stochastic process, Markov property, and transition probability, side by side with notions of biochemical reaction networks. This leads to an intuitive presentation guided by a series of biological examples that are revisited throughout the text. The text shows how the notion of propensity, the chemical master equation and the stochastic simulation algorithm arise as consequences of the Markov property. The nontrivial relationships between various stochastic approaches are derived and illustrated. The text contains many illustrations, examples and exercises to communicate methods and analyses. Matlab code to simulate cellular systems is also provided where appropriate and the reader is encouraged to experiment with the examples and case studies provided. Senior undergraduate and graduate students in applied mathematics, the engineering and physical sciences as well as researchers working in the areas of systems biology, theoretical and computational biology will find this text useful HTTP:URL=https://doi.org/10.1007/978-1-4614-0478-1

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